Windows Management Instrumentation
Windows Management Instrumentation (WMI) is a Windows administration feature that provides a uniform environment for local and remote access to Windows system components. It relies on the WMI service for local and remote access and the server message block (SMB)  and Remote Procedure Call Service (RPCS)  for remote access. RPCS operates over port 135. 
An adversary can use WMI to interact with local and remote systems and use it as a means to perform many tactic functions, such as gathering information for Discovery and remote Execution of files as part of Lateral Movement. 
Disabling WMI or RPCS may cause system instability and should be evaluated to assess the impact to a network. By default, only administrators are allowed to connect remotely using WMI. Restrict other users who are allowed to connect, or disallow all users to connect remotely to WMI. Prevent credential overlap across systems of administrator and privileged accounts. 
Monitor network traffic for WMI connections; the use of WMI in environments that do not typically use WMI may be suspect. Perform process monitoring to capture command-line arguments of "wmic" and detect commands that are used to perform remote behavior. 
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