Command and control (C2) information is encoded using a standard data encoding system. Use of data encoding may be to adhere to existing protocol specifications and includes use of ASCII, Unicode, Base64, MIME, UTF-8, or other binary-to-text and character encoding systems.   Some data encoding systems may also result in data compression, such as gzip.
For C2 over HTTP, Helminth encodes data with base64 and sends it via the "Cookie" field of HTTP requests. For C2 over DNS, Helminth converts ASCII characters into their hexadecimal values and sends the data in cleartext.
Network intrusion detection and prevention systems that use network signatures to identify traffic for specific adversary malware can be used to mitigate activity at the network level. Signatures are often for unique indicators within protocols and may be based on the specific obfuscation technique used by a particular adversary or tool, and will likely be different across various malware families and versions. Adversaries will likely change tool C2 signatures over time or construct protocols in such a way as to avoid detection by common defensive tools. 
Analyze network data for uncommon data flows (e.g., a client sending significantly more data than it receives from a server). Processes utilizing the network that do not normally have network communication or have never been seen before are suspicious. Analyze packet contents to detect communications that do not follow the expected protocol behavior for the port that is being used. 
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