Adversaries may target and collect data from local system sources, such as file systems, configuration files, or local databases. This can include sensitive data such as specifications, schematics, or diagrams of control system layouts, devices, and processes.
Adversaries may do this using Command-Line Interface or Scripting techniques to interact with the file system to gather information. Adversaries may also use Automated Collection on the local system.
ACAD/Medre.A collects information related to the AutoCAD application. The worm collects AutoCAD (*.dwg) files with drawings from infected systems. 
Duqu downloads additional modules for the collection of data from local systems. The modules are named: infostealer 1, infostealer 2 and reconnaissance. 
Flame has built-in modules to gather information from compromised computers. 
|M0803||Data Loss Prevention||
Data loss prevention can restrict access to sensitive data and detect sensitive data that is unencrypted.
|M0941||Encrypt Sensitive Information||
Information which is sensitive to the operation and architecture of the process environment may be encrypted to ensure confidentiality and restrict access to only those who need to know.  
|M0922||Restrict File and Directory Permissions||
Protect files stored locally with proper permissions to limit opportunities for adversaries to interact and collect information from the local system.  
Develop and publish policies that define acceptable information to be stored on local systems.
|ID||Data Source||Data Component||Detects|
Monitor executed commands and arguments that may search and collect local system sources, such as file systems or local databases, to find files of interest and sensitive data. Remote access tools with built-in features may interact directly with the Windows API to gather data. Data may also be acquired through Windows system management tools such as Windows Management Instrumentation and PowerShell.
Monitor for unexpected/abnormal access to files that may be malicious collection of local data, such as user files (e.g., .pdf, .docx, .jpg, .dwg ) or local databases.
|DS0009||Process||OS API Execution||
Monitor for API calls that may search local system sources, such as file systems or local databases, to find files of interest and sensitive data.
Monitor for newly executed processes that may search local system sources, such as file systems or local databases, to find files of interest and sensitive data.
Monitor for any suspicious attempts to enable scripts running on a system. If scripts are not commonly used on a system, but enabled, scripts running out of cycle from patching or other administrator functions are suspicious. Scripts should be captured from the file system when possible to determine their actions and intent. Data may also be acquired through Windows system management tools such as Windows Management Instrumentation and PowerShell.